Publications by authors named "Matthew D Voss"
Article Synopsis
- Researchers are expanding the structure-activity relationship (SAR) of quinoline compounds within the dihydropyrrolopyrazole series.
- Compound 15d, also known as LY2109761, has shown antitumor efficacy combined with good oral bioavailability.
- The study validates using pharmacokinetic/pharmacodynamic (PK/PD) approaches in vivo as effective for assessing tumor inhibition and potential antitumor efficacy.
