Publications by authors named "Matthew D'ambrosio"
Article Synopsis
- - Systemic sclerosis (SSc) is an autoimmune disease that leads to issues like blood vessel dysfunction, immune system problems, and widespread tissue scarring, but studying it has been tough due to a lack of relevant research models.
- - Researchers created an innovative in-vitro model using induced pluripotent stem cell-derived mesenchymal cells (iSCAR) to mimic the scarring seen in SSc, allowing for detailed investigation of gene expression tied to scarring at different stages.
- - The study confirms that the iSCAR model can be effectively used to test antifibrotic drugs, demonstrating responses to different compounds and revealing significant insights into the genes involved in both early and late stages of fibrosis.
Patella fracture outcomes are positive overall; however, in some cases, traditional fixation methods result in complications, including loss of fixation and irritable hardware requiring removal. We present a technique of plate fixation that we believe has the potential to improve stability and is less offensive in more comminuted fracture patterns. Improved stability should allow unfettered advancement of rehabilitation without concern for loss of fixation.
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- Spine fractures, often resulting from high-energy trauma, can lead to serious complications and require quick identification and treatment to reduce negative outcomes.
- This study reviewed data from over 3,300 trauma patients, focusing on 290 individuals with spine fractures, categorizing them by fracture location: cervical, thoracic, and lumbar.
- Key findings revealed significant associations between cervical fractures and head traumas, thoracic fractures with rib injuries, and lumbar fractures with various lower body injuries and a higher risk of inpatient mortality.
Takotsubo syndrome is classically characterized by apical ballooning and left ventricle akinesis associated with an underlying catecholamine surge. In patients with suspected Takotsubo syndrome, clinicians should be vigilant for acute coronary syndrome and arrhythmias. Ventricular standstill with underlying Takotsubo syndrome should be managed with a dual-chambered pacemaker to improve patient outcome.
View Article and Find Full Text PDFBelhassen tachycardia is the most common idiopathic ventricular tachycardia arising from the left ventricle, classically characterized by a right bundle branch block and left axis deviation. Vigilance for Belhassen tachycardia is essential as intravenous verapamil has proven to be highly efficacious for treating symptomatic patients with this underlying arrhythmia.
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