Threat exposure moderates associations between neural and physiological indices of emotion reactivity in adolescent females.

Early life adversity (ELA) characterized by threat (e.g., abuse, witnessing violence) impacts neural and physiologic systems involved in emotion reactivity; however, research on how threat exposure impacts the interplay between these systems is limited.

An RDoC-based approach to adolescent self-injurious thoughts and behaviors: The interactive role of social affiliation and cardiac arousal.

Recent theoretical models have posited that increases in self-injurious thoughts and behaviors (SITBs) during adolescence may be linked to failures in biological stress regulation in contexts of social stress. However, there is a lack of data examining this hypothesis during the transition to adolescence, a sensitive period of development characterized by changes across socioaffective and psychophysiological domains. Building on principles from developmental psychopathology and the RDoC framework, the present study used a longitudinal design in a sample of 147 adolescents to test whether interactions among experiences of social (i.

Measuring peer influence susceptibility to alcohol use: Convergent and predictive validity of a new analogue assessment.

Research on peer socialization rarely examines individual differences in adolescents' susceptibility to peer influence, perhaps because few theories or methods have elucidated how susceptibility is operationalized. This study offers a new analogue measure of peer influence susceptibility in adolescence that is adapted from sociological theory. A preliminary examination of this new paradigm included the study of individual differences in susceptibility to peer influence, convergent validity correlates, and predictive validity by examining decision-making on the task as a moderator of the prospective association between friends' and adolescents' engagement in one form of real-world risk taking.

When patients' priorities conflict with those of their medical team; a challenging case of a bleeding patient and his dying pet.

We present an unusual case of an acutely unwell patient with an upper gastrointestinal bleed whose resuscitation efforts were delayed by the discovery of his, similarly, acutely unwell pet on the medical high dependency unit. We highlight the challenges this provided the clinical team and focus on the issues relating to patient safety, consent and multidisciplinary action which may be more relevant to daily clinical practice.

Maternal morbidity: how to reduce it.

Purpose Of Review: Internationally there has been increased interest in maternal morbidity; both as a strategy to reduce maternal deaths and also because of the significant impact on a woman's life as a result of suffering from maternal morbidity. The present review will evaluate the current knowledge of, and strategies to reduce maternal morbidity.

Recent Findings: The study of maternal morbidity and how to reduce it has been hampered for many years by the lack of a standard approach to measurement and evaluation.

Determinants of Excessive Reassurance-Seeking: Adolescents' Internalized Distress, Friendship Conflict, and Inhibitory Control as Prospective Predictors.

Substantial research suggests that excessive reassurance-seeking behavior is associated with exacerbations in depressive symptoms and later interpersonal rejection, yet remarkably few studies have examined predictors of this maladaptive social behavior. This study proposed and examined a diathesis stress model suggesting that beyond the effects of prior internalized distress, a combination of poor inhibitory control and dyadic friendship conflict may be especially relevant predictors of adolescents' excessive reassurance-seeking behavior. Longitudinal associations were examined in a sample of 865 adolescents (54.

'We go to the bush to prove that we are also men': traditional circumcision and masculinity in the accounts of men who have sex with men in township communities in South Africa.

In predominantly isiXhosa-speaking township communities in South Africa, men who have sex with men negotiate their identities and sexual practices alongside heteronormative cultural scripts of what it means to be a man. Such idealised notions of masculinity are predicated on the selective appropriation of cultural practices that preserve (heterosexual) male privilege and power. In this paper, we explore the identity work done by men who have sex with men, with particular reference to male circumcision as a cultural practice widely drawn on to inform and regulate normative masculinity.

Evaluation of peracetic acid fog for the inactivation of Bacillus anthracis spore surrogates in a large decontamination chamber.

The purpose of this study was to evaluate the sporicidal (inactivation of bacterial spores) effectiveness and operation of a fogging device utilizing peracetic acid/hydrogen peroxide (PAA). Experiments were conducted in a pilot-scale 24 m(3) stainless steel chamber using either biological indicators (BIs) or bacterial spores deposited onto surfaces via aerosolization. Wipe sampling was used to recover aerosol-deposited spores from chamber surfaces and coupon materials before and after fogging to assess decontamination efficacy.

Determining the isometric point of the knee.

Posteromedial and posterolateral reconstructions of the knee are frequently required in the management of knee dislocations. This study compares the accuracy of radiographic reference points to established anatomical landmarks in reproducing the isometric points of the posteromedial corner and posterolateral corner (PLC) of the knee. Posteromedial and posterolateral surgical approaches were made in 20 cadaveric knees.

Improving illiterate patients understanding and adherence to discharge medications.

Adherence to a hospital discharge medication regime is crucial for successful treatment and to avoid increasing rates of drug resistance. A patient's success in adhering to their medication regime is dependent on many social, cultural, economic, illness and therapy-related factors, and these are often more pronounced in the developing world. Anecdotal evidence in Services Hospital, Lahore (Pakistan) suggested that the relatively high levels of illiteracy in the patient population was a major factor in poor adherence.

Pathways, outcomes, and costs in colon cancer: retrospective evaluations in two distinct databases.

Purpose: The goal of this study was to use two separate databases to evaluate the clinical outcomes and the economic impact of adherence to Level I Pathways, an evidence-based oncology treatment program in the treatment of colon cancer.

Patients And Methods: The first study used clinical records from an electronic health record (EHR) database to evaluate survival according to pathway status in patients with colon cancer. Disease-free survival in patients receiving adjuvant treatment and overall survival in patients receiving first-line therapy for metastatic disease was calculated.

Pathways, outcomes, and costs in colon cancer: retrospective evaluations in 2 distinct databases.

Objective: The goal of this study was to use 2 separate databases to evaluate the clinical outcomes and the economic impact of adherence to Level I Pathways, an evidence-based oncology treatment program in the treatment of colon cancer.

Patients And Methods: The first study used clinical records from an electronic health record (EHR) database to evaluate survival according to pathway status in patients with colon cancer. Disease-free survival in patients receiving adjuvant treatment and overall survival in patients receiving first-line therapy for metastatic disease was calculated.

Septic knee-induced deep venous thrombosis in a young adult.

This article describes a case of a 26-year-old man presenting with left knee pain of 1 week's duration, fever, and acute onset of shortness of breath the day of admission. An arthrocentesis of the knee joint was grossly positive for methicillin-resistant Staphylococcus aureus. A left lower extremity venous duplex showed thrombosis of the superficial femoral, popliteal, posterior tibial, peroneal, and gastrocnemius veins.

Adsorption of chlorine dioxide gas on activated carbons.

Research and field experience with chlorine dioxide (ClO2) gas to decontaminate structures contaminated with Bacillus anthracis spores and other microorganisms have demonstrated the effectiveness of this sterilant technology. However, because of its hazardous properties, the unreacted ClO2, gas must be contained and captured during fumigation events. Although activated carbon has been used during some decontamination events to capture the ClO2 gas, no data are available to quantify the performance of the activated carbon in terms of adsorption capacity and other sorbent property operational features.

Diabetic neuroarthropathy of the shoulder.

Neuroarthropathy of the foot and ankle is a relatively common complication of diabetes mellitus. Likewise, neuroarthropathy of the shoulder has been well reported in relation to syringomyelia. Diabetes mellitus, however, has rarely been reported to cause neuroarthropathy of any joint in the upper extremity and has never previously been reported in the shoulder.

Numerical modeling of emulsified oil distribution in heterogeneous aquifers.

In situ anaerobic bioremediation using edible oil emulsions will be most effective if the oil droplets can be brought into close contact with the contaminant to be treated. However, uniformly distributing oil in heterogeneous aquifers can be difficult. The impact of injection conditions on emulsion distribution in a three-dimensional heterogeneous aquifer is examined using MODFLOW and RT3D.

No ice, no butter.

Preview It is often difficult to determine the true extent of a burn, but most small thermal burns can be easily evaluated and managed by primary care physicians. In this article, the authors review the characteristics of different types of bums, describe those that require treatment in a bum center, and discuss appropriate measures to hasten healing and promote a satisfactory cosmetic outcome.