Publications by authors named "Matthew Cagley"

Article Synopsis
  • Image segmentation of the liver is crucial for liver cancer treatment planning, but manual methods are impractical due to scale, leading to a shift towards deep learning models for automation.
  • This study focuses on developing a generalizable deep learning model that segments the liver in T1-weighted MR images using three architectures: nnUNet, PocketNet, and Swin UNETR, with data from six different institutions totaling 819 images.
  • The results show that nnUNet and PocketNet achieved high similarity scores in liver segmentation, suggesting they can effectively perform segmentation on a diverse dataset, benefiting both intra- and inter-institutional applications.
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Article Synopsis
  • Image segmentation is crucial for treating liver cancer, but doing it manually on a large scale is impractical, so deep learning models are increasingly used for automation.
  • This study focuses on developing a deep learning model using T1w MR images to enhance liver segmentation, evaluating three different architectures with data from 819 images across six datasets.
  • The nnUNet model showed strong performance, achieving over 90% in Dice-Sorensen similarity coefficients, indicating that it can effectively segment livers even with variations in imaging techniques and disease types.
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Background And Aims: Limited methods exist to accurately characterize the risk of malignant progression of liver lesions. Enhancement pattern mapping (EPM) measures voxel-based root mean square deviation (RMSD) of parenchyma and the contrast-to-noise (CNR) ratio enhances in malignant lesions. This study investigates the utilization of EPM to differentiate between HCC versus cirrhotic parenchyma with and without benign lesions.

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Background: Outcomes after definitive chemoradiation for squamous cell carcinoma are generally favorable. However, biomarkers to further yield prognostic information are desired. Treatment-related lymphopenia as well as an elevated baseline neutrophil-lymphocyte ratio have been associated with worse survival in several cancer types.

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