Publications by authors named "Matthew C Pertzborn"

Cystic Fibrosis (CF) care has advanced tremendously in the United States (US), North America, Australasia, and Europe in recent decades. Given the concern for global disparities in pediatric medical care in other parts of the world, we wanted to assess the availability of key aspects of current pediatric CF care in the Middle East as-compared to the US. We collected electronic surveys from pediatric CF providers in the Middle East and surrounding countries assessing whether treatments known to be widely available in the US were also available in surveyed countries.

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Background: Inhaled corticosteroids (ICSs) are a fundamental pillar of most regimens for long-term control of persistent asthma. Poor adherence to ICS medication is a common problem in the asthma population that can lead to poor asthma control. We hypothesized that conducting a follow-up telephone call after general pediatric clinic visits for asthma would improve refill persistence.

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Article Synopsis
  • Recurrent laryngeal afferent fibers trigger cough responses to stimuli in the upper trachea and larynx of guinea pigs, while lower airway receptors may influence this reflex.
  • A study on cats undergoing vagotomy (cutting the vagus nerve) showed that it substantially reduced cough from both mechanical stimulation in the lower airway and chemical stimulation (like capsaicin).
  • The findings highlight the role of sensory feedback from the lower airways and pulmonary receptors in facilitating cough responses in cats.
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Background And Objectives: The albuterol dropper bottle used to prepare solutions for continuous nebulization contains the preservative benzalkonium chloride (BAC). BAC, by itself, has been shown to cause bronchospasm. We hypothesized that BAC would decrease the therapeutic efficacy of albuterol in patients with acute asthma exacerbations.

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Poor adherence with inhaled corticosteroid (ICS) medication is common in the pediatric population and can result in poor asthma control with increased frequency of asthma-related complications. The purpose of this study was to determine whether or not the initiation of ICS administration twice per day at school/daycare in patients with poor medication adherence at home improves asthma health care outcomes. We retrospectively selected patients followed by our Pediatric Pulmonology Clinic who had poorly controlled asthma and had been assigned to receive ICS twice daily at school/daycare due to poor adherence with ICS therapy.

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Synopsis of recent research by authors named "Matthew C Pertzborn"

  • - Matthew C Pertzborn's research primarily focuses on pediatric respiratory conditions, particularly cystic fibrosis and asthma, highlighting the disparities in care and adherence issues faced by children in diverse socioeconomic settings.
  • - Recent studies indicate significant challenges in pediatric cystic fibrosis management in the Middle East, revealing gaps in treatment availability compared to established care practices in the US.
  • - Pertzborn's work also emphasizes the importance of post-visit outreach strategies to improve medication adherence in young asthma patients, suggesting that follow-up interventions can enhance refill persistence and overall health outcomes.