Publications by authors named "Matteo Padroni"

Our aim was to evaluate osteomyelitis and other major lower limb safety outcomes (i.e., peripheral artery disease or PAD, ulcers, atraumatic fractures, amputations, symmetric polyneuropathy, and infections) in patients affected by type 2 diabetes mellitus (T2DM) and treated with sodium-glucose cotransporter 2 inhibitors (SGLT2-is).

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Article Synopsis
  • The IASP ICD-11 defines chronic primary pain (CPP) and notes increasing interest in cannabinoids as a treatment, though evidence for their efficacy in CPP is limited.
  • This systematic review aims to analyze the effectiveness and safety of cannabinoids for managing CPP by reviewing randomized controlled trials and other studies.
  • The review included eight studies from 3007 records, focusing on outcomes like pain reduction, quality of life, and various mental health aspects, along with assessing safety and potential biases.
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The aerosol performance and delivery characteristics of tobramycin for the treatment of respiratory infection were evaluated using the Orbitalâ„¢, a multi-breath, high dose, dry powder inhaler (DPI). Micronised tobramycin was prepared and tested in the Orbital and in the commercially available TOBI Podhaler (Novartis AG). Furthermore, the TOBI Podhaler formulation containing tobramycin as Pulmospheres was tested in both the commercial Podhaler device (T-326) and Orbital for comparison.

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