Publications by authors named "Matteo Giacomini"
Article Synopsis
- Automated analysis of lung CT scans can help classify different subphenotypes of acute respiratory illness in COVID-19 patients by combining CT features with clinical and lab data.
- A study of 559 spontaneously breathing COVID-19 patients identified two subphenotypes: one with older patients, higher inflammation, more severe hypoxemia, and a higher mortality rate, while the other had distinct lung imaging features and lower mortality.
- The findings emphasize the potential of using machine learning and lung-CT imaging to improve the understanding and treatment of respiratory failure in COVID-19 patients.
Article Synopsis
- Lung problems in COVID-19 can cause serious issues, like kidney injury, especially in patients on mechanical ventilation.
- In a study with 157 patients, nearly half developed acute kidney injury (AKI), with most having it persist over time.
- Higher ventilation levels were linked to more severe kidney issues, suggesting that problems with blood flow might connect the lung and kidney problems in COVID-19 patients.
Background: Patients with high spinal cord injury (SCI) are unable to breathe on their own and require mechanical ventilation (MV). The long-term use of MV is associated with increased morbidity and mortality. In patients with intact phrenic nerve function, patients can be partially or completely removed from MV by directly stimulating the diaphragm motor points with a diaphragm pacing system (DPS).
View Article and Find Full Text PDFBackground: The performances of 2 noninvasive CPAP systems (high flow and low flow air-entrainment masks) were compared to the Boussignac valve in 3 different scenarios.
Methods: Scenario 1: pneumatic lung simulator with a tachypnea pattern (tidal volume 800 mL at 40 breaths/min). Scenario 2: Ten healthy subjects studied during tidal breaths and tachypnea.
Descending necrotising mediastinitis is a severe infection spreading from the cervical region to the mediastinal connective tissue. It represents a virulent form of mediastinal infection, requiring prompt diagnosis and treatment to reduce the high mortality associated. An optimal debridement and drainage through an open thoracotomy access are the keys for a successful outcome.
View Article and Find Full Text PDFStudy Objectives: Noninvasive ventilation, although effective as treatment for patients with acute cardiogenic pulmonary edema when prolonged for hours, is of limited use in the emergency department (ED). The aim of the study was to determine whether a short attempt at noninvasive pressure support ventilation avoids ICU admittance and to identify lack of response prediction variables.
Design: Prospective inception cohort study.