The Impact of COVID-19 on Emergency Medicine Rotations.

Introduction The impact of modifications in curriculum and clinical rotations made secondary to the COVID-19 pandemic on medical education has yet to be fully investigated. We observed differences in the types of patients seen by medical students that may have resulted from clinical disruptions due to the COVID-19 pandemic. We then evaluated what impact these disruptions had on the students' clinical competency.

Subcutaneous Sweet Syndrome Presenting as Cellulitis in a Pregnant Female.

We report a case of subcutaneous Sweet syndrome in a pregnant woman that was initially believed to be cellulitis. She was admitted after failure of symptom resolution following multiple oral antibiotics as an outpatient. Her rash continued to progress, and she became nauseous with a lack of appetite.

The Effect of Behavioural Indicators of Calf Discomfort Following Routine Procedures on Cow Maternal Care.

Pain causes altered arousal and specific behaviours that are rare at other times (pain indicators). We examined whether beef cows (mean age 6 years) are sensitive to pain indicators in addition to arousal following ear tagging and rubber ring castration (males only, = 31) of their calf ( = 58). Behavioural pain indicators and activity were recorded continuously for 20 min before and 2 h after handling.

Structural basis for alpha-conotoxin potency and selectivity.

Parkinson's disease is a debilitating movement disorder characterized by altered levels of alpha(6)beta(2) * ( * indicates the possible presence of additional subunits) nicotinic acetylcholine receptors (nAChRs) localized on presynaptic striatal catecholaminergic neurons. alpha-Conotoxin MII (alpha-CTx MII) is a highly useful ligand to probe alpha(6)beta(2) nAChRs structure and function, but it does not discriminate among closely related alpha(6) * nAChR subtypes. Modification of the alpha-CTx MII primary sequence led to the identification of alpha-CTx MII[E11A], an analog with 500-5300-fold discrimination between alpha(6) * subtypes found in both human and non-human primates.