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Publications by authors named "Matt R Kelley"

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Synopsis of recent research by authors named "Matt R Kelley"

  • - Matt R Kelley’s research primarily focuses on the role of the K/Cl cotransporter KCC2 in neuronal function and its implications for epilepsy, particularly how KCC2 activity affects GABAergic inhibition and the development of epilepsy-related conditions.
  • - His studies investigate the critical requirement of KCC2 for mature neuron survival and highlight that compromised KCC2 function can lead to heightened neuronal excitability and contribute to the pathophysiology of temporal lobe epilepsy.
  • - Kelley also explored the therapeutic potential of targeting KCC2 in epilepsy treatment, as well as developed human induced neural stem cell lines that may enhance research and applications in neurobiology and tissue engineering.

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