Publications by authors named "Matt McGee"
Article Synopsis
- The Zika virus (ZIKV) is a significant human pathogen, and previous research has highlighted antibodies from Zika patients that target specific regions on the virus's envelope proteins, known as E dimer epitopes (EDE).
- The study involved immunizing mice with ZIKV components and analyzing their immune response, particularly the ability of antibodies to bind to specific viral epitopes and neutralize the virus in laboratory tests.
- Findings indicate that both human Zika patient sera and mouse antibodies can recognize and neutralize ZIKV by binding to different forms of the glycan loop on envelope proteins, leading to a new classification of these antibodies into EME1 and EME2 based on their glycan-binding requirements.
