Publications by authors named "Matt J Budoff"
Objective: To characterize the spatio-temporal association between features of the built environment and subclinical liver disease.
Design: We used data from a large community-based population, the Multi-Ethnic Study of Atherosclerosis (2000-2002, N = 5542) with linked historical residential data that characterized past exposure to alcohol outlets (bars and liquor stores), healthy foods stores, and physical activity facilities (1990-2001). We examined whether and how past residential relate to hepatic steatosis (proxied by liver attenuation measured using computed tomography, with lower attenuation indicating higher hepatic steatosis).
Article Synopsis
- People with HIV (PWH) are more likely to develop diastolic dysfunction, and this study investigates the relationship between different types of body fat and heart function in men both with and without HIV.
- Using echocardiography and CT scans, the study assessed various fat deposits, finding that greater epicardial fat was linked to increased chances of diastolic dysfunction, while less subcutaneous fat was also a risk factor.
- The results indicate that both higher epicardial adipose tissue and lower subcutaneous adipose tissue contribute to diastolic dysfunction, regardless of a person's HIV status and whether they are virally suppressed.
Background And Objectives: Osteoprotegerin (OPG), a cytokine that regulates bone resorption, has been implicated in the process of vascular calcification and stiffness.
Design, Setting, Participants, & Measurements: Serum OPG was measured in 351 participants with chronic kidney disease (CKD) from one site of the Chronic Renal Insufficiency Cohort Study. Cortical bone mineral content (BMC) was measured by quantitative computed tomography in the tibia.