Leadless pacemakers reduce risk of device-related infection: Review of the potential mechanisms.

Pacemaker-related infections remain a constant concern due to increased risk of patient morbidity and mortality. Although transvenous pacemakers are expected to have an infection rate ranging from 0.77% to 2.

Reduced bacterial adhesion with parylene coating: Potential implications for Micra transcatheter pacemakers.

Introduction: Infections of cardiac implantable electronic devices remain a prevalent health concern necessitating the advent of novel preventative strategies. Based on the observation that bacterial infections of the Micra transcatheter pacemaker device are extremely rare, we examine the effect of parylene coating on bacterial adhesion and growth.

Methods: Bacterial growth was compared on polyurethane coated, bare, or parylene coated titanium surfaces.

Distal right ventricular coil position reduces defibrillation thresholds.

Unlabelled: Distal RV Coil Position Reduces DFTs.

Introduction: Understanding the factors that affect defibrillation thresholds (DFTs) has important implications both for optimization of defibrillation efficacy and for the design of new transvenous leads. The aim of this prospective study was to test the hypothesis that defibrillation efficacy is improved with the right ventricular (RV) coil in a distal position compared with a more proximal RV coil position.