Publications by authors named "Matsuzuka T"
Article Synopsis
- Recent advancements in chemotherapy have improved survival rates for head and neck cancer patients, leading to the development of totally implantable venous access devices for chemotherapy use.
- A study investigated 210 patients who had these devices implanted in their upper arms over a decade, examining their effectiveness for treatment and any associated adverse events.
- The results showed a low adverse event rate, with certain factors like non-ultrasound-guided puncture increasing risks, suggesting that using ultrasound guidance may enhance safety in these procedures.*
Article Synopsis
- Researchers conducted a study to explore the connection between thyroid autoantibodies (Tabs) and the clinical profiles of young patients (ages 3-29) with thyroid nodules, using data from 3,018 participants in the Fukushima Health Management Survey.
- The study discovered that Tabs were found in 13.9% of participants, with higher rates in females, those with diffuse goiter, and those diagnosed with papillary thyroid carcinoma.
- Findings indicate that Tab positivity is linked to larger thyroid sizes, the presence of diffuse goiter and papillary thyroid carcinoma, and high TSH levels, suggesting that testing for Tabs could enhance assessment methods for thyroid function and cancer detection in younger patients with nodules.
Article Synopsis
- The primary cause of diffuse thyroid goiter is Hashimoto's thyroiditis, an autoimmune disorder, which is important for children's growth and development.
- A study analyzed data from over 320,000 participants aged 1-23 to investigate the connections between diffuse goiter, thyroid volume, and body measurements, finding that diffuse goiter is more common in females as they age.
- Results indicated that higher body mass index (BMI) and the presence of nodules are linked to an increased prevalence of diffuse goiter, particularly reflecting age-related trends in younger populations.
Article Synopsis
- - The study aimed to identify when sentinel lymph node biopsy (SLNB) is appropriate for treating oral cancer with no lymph node involvement.
- - Researchers analyzed data from 158 patients focusing on the depth of invasion (DOI) and long diameter (LD) of tumors to determine the rates of SLN metastasis.
- - Findings showed varying SLN positivity rates based on tumor size, suggesting that SLNB could be a valuable method for managing lymph nodes in patients with oral cancer.
Article Synopsis
- The Fukushima Prefecture introduced a Thyroid Ultrasound Examination program for residents aged 0-18 to address health concerns associated with radiation exposure after the earthquake.
- A total of 242,065 individuals were surveyed, revealing varying detection rates of thyroid cancer across four regions, with notable differences based on sex, age, and the timing of surveys.
- The study highlighted potential biases in participation and diagnostic processes, emphasizing that these confounding factors should be taken into account in future research on thyroid cancer detection rates.
This sentinel node (SN) biopsy trial aimed to assess its effectiveness in identifying predictive factors of micrometastases and to determine whether elective neck dissection is necessary in oral squamous cell carcinoma. This retrospective study included 55 patients from three previous trials, with positive SNs. The relationship between the sizes of the metastatic focus and metastasis in non-sentinel node (NSN) was investigated.
View Article and Find Full Text PDFBackground: A multicenter, randomized controlled phase III trial was conducted on sentinel lymph node biopsy (SLNB) and elective neck dissection for T1 (depth of invasion ≥ 4 mm)-T2N0M0 oral cavity squamous cell carcinoma. This study identified factors associated with poor prognosis in patients who underwent SLNB based on a subgroup analysis of this trial.
Methods: We analyzed 418 sentinel lymph nodes (SLNs) from 132 patients who underwent SLNB.
We previously described the thyroid volume, which was calculated by measuring the thyroid width, thickness, and longitudinal length using ultrasonography, in children and adolescents. We have proposed a simplified method for quantitatively assessing the thyroid size, to overcome the inaccuracy and challenges in measuring the longitudinal length of the thyroid. Based on measurements of 317,847 (girls: 156,913, boys: 160,934) children and adolescents, we calculated sex-specific means and standard deviations of thyroid width and thickness, and of the cross-sectional area computed by multiplying them, for every age and 0.
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- The Great East Japan Earthquake in 2011 and the resulting tsunami led to a nuclear accident at the Fukushima Daiichi Nuclear Power Plant, causing significant radioactive contamination.
- In response to health concerns, especially for children aged 0-18, Fukushima launched the Thyroid Ultrasound Examination (TUE) program to detect thyroid nodules and cysts.
- Findings indicated that while some cases were diagnosed as malignant, the increased childhood thyroid cancer rates were likely due to improved detection methods rather than radiation exposure, highlighting issues with overdiagnosis and the need for psychological support for families.
Article Synopsis
- Low thyrotropin (TSH) levels were observed in children and adolescents with thyroid nodules, contrasting the adult trend where high TSH levels are a risk factor for nodules.
- The study involved analyzing thyroid hormone responsiveness in 4,955 participants, particularly focusing on young individuals (6-20 years) with and without thyroid nodules.
- Findings indicated that the responsiveness of TSH to thyroid hormones decreases with age and varies by sex, with significant associations between low TSH and the presence of nodules noticed in participants aged 12 to 17.
Purpose: Squamous cell carcinoma of the maxillary sinus (SCC-MS) is often diagnosed at a locally advanced stage, which is associated with poor prognosis. The purpose of the present study was to investigate clinical outcomes in patients with locally advanced T4 SCC-MS including originally inoperable T4b disease treated with neoadjuvant superselective intra-arterial chemoradiotherapy combined with surgery.
Methods: This study is a retrospective case series.
Objective: The localization pattern of metastatic sentinel lymph node (SN) and non-SNs and pathologic analysis of metastatic lymph nodes in SN lymphatic basin dissection (SLBD) were investigated in patients with cT2/T3cN0 oral squamous cell carcinoma (OSCC).
Methods: This prospective multicenter trial involved 10 institutions nationwide in Japan. A total of 57 patients were enrolled.
The thyroid ultrasound examination (TUE) program was initiated among the residents of Fukushima Prefecture aged ≤18 years at the time of the Fukushima Dai-ichi Nuclear Power Plant accident. In this program, fine needle aspiration cytology (FNAC) was performed only in cases that conformed to the Japanese guidelines for the management of thyroid nodules. To analyze the suitability of the protocol in the TUE, we analyzed the implementation rate of FNAC and the detection rate of thyroid malignancy.
View Article and Find Full Text PDFArticle Synopsis
- The study examines the impact of the Thyroid Ultrasound Examination (TUE) program in Fukushima, highlighting the creation of a Thyroid Support Team aimed at alleviating anxiety for examinees and their families.
- An analysis of 223 records shows that common concerns during first visits include the TUE program and examination findings, with the support team providing essential information and reassurance.
- Results indicate that psychosocial support successfully reduced anxiety levels for both examinees and their families, with family members typically experiencing higher anxiety, highlighting the need for ongoing support amid changing social conditions.
Purpose: This study aimed to compare patients with early oral cavity squamous cell carcinoma (OCSCC) (tumor category [T] 1-2, node-negative, and no distant metastasis) treated with traditional elective neck dissection (ND) with those managed by sentinel lymph node biopsy (SLNB) using survival and neck function and complications as end points.
Methods: Sixteen institutions in Japan participated in the study (trial registration number: UMIN000006510). Patients of age ≥ 18 years with histologically confirmed, previously untreated OCSCC (Union for International Cancer Control TNM Classification of Malignant Tumors 7th edition T1-2, node-negative no distant metastasis), with ≥ 4 mm (T1) depth of invasion, were randomly assigned to undergo standard selective ND (ND group; n = 137) or SLNB-navigated ND (SLNB group; n = 134).
Objective: The aim of this supplemental study of a sentinel node (SN) biopsy (SNB) trial for oral squamous cell carcinoma (OSCC) was to assess the effectiveness in identifying micrometastasis and determining whether elective neck dissection (END) is necessary.
Materials And Methods: Twenty-three patients with pathologically positive SNs were included. The sizes of the metastatic lesions in positive SNs (SMSNs) were classified and the rates of occult metastasis of non-SNs were compared.
Objective: Although eating disorders (EDs) surged in the late 1900s and are now recognized worldwide, the time trend of ED characteristics remains unknown. This study aimed to clarify changes in characteristics of anorexia nervosa restricting type (AN-R) over 30 years.
Methods: We conducted a cross-sectional study and examined 996 female treatment-seeking patients with AN-R in Japan from 1988 to 2018.
The Fukushima Daiichi Nuclear Power Plant accident occurred on March 11 2011, following the Great East Japan Earthquake and tsunami. Radioactive materials, including I-131, were released into the environment after the accident. Shortly after, the prefectural government initiated the Fukushima Health Management Survey for monitoring the long-term health conditions of the residents of Fukushima Prefecture.
View Article and Find Full Text PDFObjectives: The risk of aspiration pneumonia has been reported to increase with age, especially in elderly residents of nursing homes. However, the characteristics of those with swallowing impairments at elderly care facilities have not yet been evaluated using reliable instrumental examinations. The aims of the current study were to investigate the frequency of swallowing impairment and determine the characteristics of the elderly with swallowing disorders residing at care facilities.
View Article and Find Full Text PDFThe identification of thyroid cancers among children after the Chernobyl nuclear power plant accident propelled concerns regarding long-term radiation effects on thyroid cancer in children affected by the Fukushima Daiichi nuclear power plant accident in Fukushima, Japan. Herein we consider the potential association between absorbed dose in the thyroid and the risk of developing thyroid cancer as detected by ultrasonography on 300 473 children and adolescents aged 0-18 years in Fukushima. The absorbed dose mentioned in the present study indicates the sum of that from external exposure and that from internally deposited radionuclides.
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- The Great East Japan Earthquake in 2011 led to the establishment of the Thyroid Ultrasound Examination (TUE) program to evaluate health impacts in Fukushima due to radiation exposure.
- A study conducted at Fukushima Medical University identified 11 cases of thyroid cancer that were not detected by the TUE program, representing 5.7% of the total diagnosed cases.
- The characteristics of these "outside" cases were similar to those identified through the TUE program, suggesting that the program is effective in detecting thyroid cancer among residents.
Background: The 2011 Great East Japan Earthquake led to a nuclear accident at Fukushima Daiichi Nuclear Power Plant. This study examines the associations of radiation dose and lifestyle factors with incidence of thyroid cancer in Fukushima.
Methods: We designed a prospective study with 300,473 participants aged 18 years or younger, who underwent thyroid examinations from October 2011.
Article Synopsis
- A retrospective study investigated a new method called "FEES screen," which assesses swallowing impairment severity without introducing food or liquid, reducing the risk of aspiration-related complications.
- The study analyzed 106 subjects with swallowing issues, categorizing them into undetectable (USI) and detectable (DSI) impairment groups based on results from conventional FEES.
- Findings revealed that the DSI group had higher rates of aspiration and greater care needs, indicating that FEES screen can effectively identify individuals at risk and help tailor interventions.
Objectives: This study focused on parotid gland tumours diagnosed as benign by fine-needle aspiration cytology and investigated the necessity of frozen section biopsy.
Methods: There were 104 cases of parotid gland tumour where fine-needle aspiration cytology was benign and frozen section biopsy was subsequently performed, between April 2006 and June 2016. In this retrospective study, the results of frozen section biopsy were analysed and compared with the final histological diagnosis.