Objective: Anti-aminoacyl-tRNA synthetase (anti-ARS) antibodies are useful for identifying a clinical subset of patients with idiopathic inflammatory myopathies (IIMs). Anti-OJ antibodies, which recognize multi-enzyme synthetase complexes including isoleucyl-tRNA synthetase (IARS) and lysyl-tRNA synthetase (KARS), are among the anti-ARS antibodies. Although testing antibodies to other ARSs have been used clinically, no validated immunoassays for detecting anti-OJ antibodies are available.
View Article and Find Full Text PDFKansenshogaku Zasshi
November 1984
Antimicrob Agents Chemother
September 1973
The activities of penicillinase inhibitor, KA-107 extracted from culture filtrates of Streptomyces gedanensis ATCC 4880, were studied by using penicillin-resistant S. aureus FS-1277 and by means of in vitro and in vivo tests.
View Article and Find Full Text PDFMycopathol Mycol Appl
December 1970
Antimicrob Agents Chemother (Bethesda)
January 1968
Kitasato Arch Exp Med
December 1965
J Antibiot (Tokyo)
September 1965
Kitasato Arch Exp Med
December 1964