[Changes in the C-peptide concentration in the blood of patients with diabetes mellitus after the transplantation of cultures of pancreatic islet cells].

The time course of the blood level of C-peptide was studied in 20 patients with insulin dependent diabetes mellitus in the course of 1 year after human fetal pancreatic islet cell allotransplantation. All the recipients suffered from a labile type of diabetes complicated by polyneuropathy, glomerulosclerosis and progressive retinopathy. C-peptide concentration was determined by a radioimmunoassay using Behring-Werke AE kits (FRG).