Right Coronary Sinus of Valsalva Aneurysm Rupture Precipitated by Nonsyndromic Aortopathy.

We present a case highlighting the diagnostic challenges of identifying a ruptured right coronary sinus of Valsalva aneurysm in a patient with nonsyndromic aortopathy. Timely assessment with transthoracic and transesophageal echocardiography is vital for prompt diagnosis and successful treatment. Genetic panel testing should be offered to probands and first-degree family members.

Alterations in Layer-Specific Left Ventricular Global Longitudinal and Circumferential Strain in Patients With Aortic Stenosis: A Comparison of Aortic Valve Replacement versus Conservative Management Over a 12-Month Period.

Background: Impairment in left ventricular (LV) systolic strain in aortic stenosis (AS) is well documented. However, alterations in layer-specific LV global longitudinal strain (GLS) and global circumferential strain (GCS) and their recovery following surgical aortic valve replacement (AVR) have not been established. The aim of this study was to examine layer-specific changes in GLS and GCS in patients with AS undergoing AVR and compare these patients with those managed conservatively over 12 months.

Left atrial function: Correlation with left ventricular function and contractile reserve in patients with hypertension.

Aims: Alterations in left atrial (LA) and left ventricular (LV) function have been documented in hypertensive patients. However, the correlation of LA with LV functional changes has not been established. Using normotensive controls, we examined LA functional changes in hypertensive patients by strain deformation analysis, and their relationship to LV functional changes including contractile reserve (CR).

Left ventricular function and contractile reserve in patients with hypertension.

Aims: An impaired contractile reserve (CR) may be an early manifestation of left ventricular (LV) systolic dysfunction in hypertensive patients. Using normotensive patients as controls, we examined LV CR and its correlates in hypertensive patients.

Methods And Results: One hundred and twenty-nine (68 men, aged 58.

Differential Myocardial Fibre Involvement by Strain Analysis in Patients With Aortic Stenosis.

Background: Aortic stenosis (AS) is the most common valvular heart disease and can result in left ventricular (LV) systolic impairment. LV myocardial fibres are organised in layers: the subendocardial layer is orientated longitudinally and the subepicardial layer circumferentially. We hypothesised that there is differential involvement of myocardial fibres in patients with aortic stenosis.