The supplementation of the angiotensin-converting enzyme inhibitor ramipril to combined therapy in patients with chronic obstructive bronchitis complicated by chronic cor pulmonale resulted in positive central, pulmonary, and peripheral hemodynamic changes, improved peripheral tissue oxygenation, by exerting beneficial effects on the course of the disease.
View Article and Find Full Text PDFThe effect of niphangin (calcium antagonist) on the hemodynamics, gaseous exchange and course of the disease was studied in 65 patients with chronic obstructive bronchitis complicated by cor pulmonale. Synchronous registration of ECG, PCG, tetrapolar rheography, phlebography. It was found that niphangin used in the complex treatment of cor pulmonale allowed to improve the gaseous exchange, central and peripheral hemodynamics and effected favourably the course of the disease.
View Article and Find Full Text PDFThe state of pulmonary circulation in patients with chronic bronchitis depends on the presence of obstruction, its progression, development of pulmonary hypertension, cor pulmonale and its decompensation. The authors recommend to administer nitrates of prolonged action to such patients.
View Article and Find Full Text PDFKinetocardiography and integral rheography of the body were used to examine the effect of nitroglycerin on the hemodynamics in 17 patients with chronic obstructive bronchitis complicated by pulmonary hypertension. The drug exerted a pronounced hypotensive action on the pressure in the pulmonary artery, increased the cardiac output at the expense of the stroke volume, reduced the resistance to the pulmonary blood flow and the peripheral vascular resistance.
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