[Iron as an inducer of nitric oxide formation in the animal body].

Citrate iron complex injections to mice or rats resulted in the nitric oxide formation detected by nitric oxide binding to iron-diethyldithiocarbomate complexes. The mononitrosyl iron complexes formed were paramagnetic and EPR active. The maximal nitric oxide concentrations in rat livers were 15-20 nm per gram of tissue.

[Effect of sodium sulfate on the microsomal oxidation system in the liver and the morphological status of the internal organs of the white rat].

The morphological state of the internal organs as well the changes of microsomal oxidation in liver of white rats exposed to the action of sodium sulfate in doses 200 and 600 mg per 100 g of body weight have been studied. The sodium sulfate in dose 600 mg per 100 g of body weight has been found to decrease the cytochrome P450 content, increase its inactivation rate and have an injurious effect on the membranes of hepatocytes. Sodium sulfate administration through the gastroenteric tract causes the destructive and pathological histochemical changes in liver, stomach, duodenum and small intestine.