Publications by authors named "Matilde Lazzari"
Purpose: To establish whether a slow or a rapid withdrawal of antiepileptic monotherapy influences relapse rate in seizure-free adults with epilepsy and calculates compliance and differences in the severity of relapses, based on the occurrence of status epilepticus, seizure-related injuries, and death.
Methods: This is a multicentre, prospective, randomized, open label, non-inferiority trial in people aged 16 + years who were seizure-free for more than 2 years. Patients were randomized to slow withdrawal (160 days) or rapid withdrawal (60 days) and were followed for 12 months.
Article Synopsis
- A study evaluated the use and effectiveness of intravenous brivaracetam (BRV) in treating status epilepticus (SE) across 24 neurology units in Italy from March 2018 to June 2020.
- Out of 56 patients analyzed, BRV was effective in resolving seizures in 57% of cases, with a notable early response (within 6 hours) observed in 39% of patients.
- The findings suggest that BRV is a safe and beneficial treatment for SE, especially when administered early after the onset of seizures.