PP050. NT-Pro-BNP: Correlation with adverse outcome markers in hypertensive gestational syndromes.

Introduction: Brain-type natriuretic peptide is released by cardiomyocites in response to parietal stress augmentation and systemic endothelial dysfunction. Hypertensive Gestational Syndromes (HGS) share this mechanism, but the correlation between NT-Pro-BNP and maternal/fetal outcomes is not yet clear enough.

Objectives: Evaluate the correlation between NT-Pro-BNP in HGS and Normotensive Pregnant Women (NPW), with clinical and biological markers of adverse maternal/fetal outcome.

Evidence of fetal pulmonary aspiration of intra-amniotic administered surfactant in animal experiment.

Introduction: The instillation of surfactant into the airways of patients with respiratory distress syndrome (RDS), especially in the neonatal period, is a proven therapy. The preventive therapy of RDS through intra-amniotic injection of surfactant has been reported recently. It has not been conclusively shown, however, that the surfactant administered in this way actually reaches the fetal pulmonary airways.