Publications by authors named "Matias Rivera"

Article Synopsis
  • The study focuses on the herbaceous species PPL, which has bioactive compounds linked to anti-inflammatory properties, suggesting it might help with chronic inflammation conditions like inflammatory bowel diseases (IBD).
  • Researchers evaluated the effects of a PPL extract on inflammatory markers in Caco-2 cells, using a specific treatment setup and advanced characterization techniques like LC-MS/MS and qRT-PCR.
  • The findings indicated that PPL extract significantly reduced mRNA and protein levels of certain inflammatory markers after 72 hours of treatment, presenting PPL as a potential complementary therapy for improving the quality of life for IBD patients.
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Type 2 diabetes mellitus (T2D) is a metabolic disorder caused by chronic hyperglycemia due to a deficiency in the secretion and/or action of insulin. Zinc (Zn) supplementation and strength exercise increases insulin signaling. We evaluate the effect of Zn supplementation and strength exercise on insulin resistance in the liver of rats with diet-induced T2D through the study of phosphorylation of Akt and protein tyrosine phosphatase 1B (PTP1B).

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Human lymphotropic virus type 1 (HTLV-1) is a retrovirus causing HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a neurodegenerative central nervous system (CNS) axonopathy. This virus mainly infects CD4(+) T lymphocytes without evidence of neuronal infection. Viral Tax, secreted from infected lymphocytes infiltrated in the CNS, is proposed to alter intracellular pathways related to axonal cytoskeleton dynamics, producing neurological damage.

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