Publications by authors named "Matias Negrotto"

Background: Pituitary incidentalomas are an occurrence documented in 10.6% of post-mortem examinations, 4%-20% of computed tomography (CT) scans, and 10%-38% of magnetic resonance imaging (MRI) cases, primarily consisting of microincidentalomas (<1 cm in size). However, the prevalence of pituitary incidentalomas in Uruguay remains unexplored.

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Modern hyperacute reperfusion therapies including intravenous thrombolysis and mechanical thrombectomy have transformed the management of arterial ischemic stroke (AIS) in adults. Multiple randomized clinical trials have demonstrated that these therapies enable remarkable improvements in clinical outcome for properly selected patients with AIS. Because pediatric patients were excluded from predicate clinical trials, there is a conspicuous lack of data to guide selection of therapies and inform age-adjusted and pathology-oriented treatment modifications for children.

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Article Synopsis
  • Definitive diagnosis of stroke subtype and etiology in children with arterial ischemic stroke (AIS) is crucial for reducing complications and preventing future strokes.
  • The causes of AIS in children differ significantly from those in adults, necessitating a thorough and structured diagnostic approach.
  • Advanced brain imaging and vascular studies are essential for diagnosis, and there are various medical and surgical strategies available for preventing secondary strokes based on the underlying causes.
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Article Synopsis
  • The initial evaluation of children suspected of having arterial ischemic stroke (AIS) is challenging due to the rarity of pediatric strokes and diverse age-related stroke types.
  • Pediatric AIS may exhibit distinct characteristics when compared to adult AIS, making it important for specialists to recognize these differences.
  • The review offers practical strategies to help stroke specialists make diagnostic decisions during the early stages of patient care.
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Background And Purpose: A well-known classification of dural arteriovenous fistulas (DAVFs) according to the patterns of venous drainage was described in 1977 by Djindjian, Merland et al. and later revised by Cognard, Merland et al. in 1995.

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Long-awaited positive trial data have shown the efficacy of endovascular treatment in patients with ischemic stroke who arrive at the hospital within the first 6 hours with large-vessel occlusion of the anterior circulation. With the introduction of stent retrievers (SRs) for mechanical thrombectomy, efficient and safe large-artery recanalization treatment can be achieved. However, sometimes there are patients who do not attain complete flow restoration following attempts with traditional maneuvers.

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Background And Purpose: Endovascular treatment of broad-neck, complex cerebral aneurysms is a challenging issue. Placement of a stent over the aneurysm neck and secondary coil embolization prevents coil migration and allows dense packing of the coils. Another challenge is represented by distal aneurysms situated in small vessels.

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