Publications by authors named "Mathurin Dembele"
Background: In sub-Saharan Africa, bovine tuberculosis (bTB) is a potential hazard for animals and humans health. The goal of this study was to improve our understanding of bTB epidemiology in Burkina Faso and especially Mycobacterium bovis transmission within and between the bovine and human populations.
Methodology/principal Findings: Twenty six M.
In theory, the removal of user fees puts health services within reach of everyone, including the very poor. When Burkina Faso adopted the DOTS strategy for the control of tuberculosis, the intention was to provide free tuberculosis care. In 2007-2008, interviews were used to collect information from 242 smear-positive patients with pulmonary tuberculosis who were enrolled in the national tuberculosis control programme in six rural districts.
View Article and Find Full Text PDFBackground: Nevirapine (NVP) plasma levels are reduced in patients receiving rifampicin (RFM) for tuberculosis (TB) treatment. We determined variations over time of the pharmacokinetic parameters of NVP in patients who receive RFM.
Methods: HIV-1-infected patients with CD4+ T-lymphocyte count
Article Synopsis
- The study aimed to evaluate the use of the GenoType MTBDRplus molecular assay to detect drug-resistant tuberculosis (DR-TB) directly from clinical samples in Burkina Faso, where resources for traditional testing are limited.
- Researchers collected sputum samples from 108 chronic TB patients over a two-year period, processing them for microscopy and DNA analysis in order to identify mutations that confer resistance to common TB drugs like rifampin and isoniazid.
- The results showed a valid test outcome for most patients, revealing various strains, including those resistant to rifampin (notably due to the D516V mutation) and instances of non-tuberculous mycobacterial infections, highlighting the need for accurate diagnostic methods