Potential Degradation of Low- and High-Density Polyethylene Films by Ochrobactrum intermedium SA1 from Sewage Sludge.

Accumulation of plastic waste is an alarming environmental concern across globe. For which, microbial degradation offers an efficient ecofriendly solution. Thus, the present study focuses on the exploration of new bacterium that can grow on and utilize polyethylene.

E-portfolio in Learning and Assessment of Community Medicine for Medical Undergraduate Students.

Background: A portfolio is a specific collection of student work and achievements in various areas. E-portfolio is an electronic collection that serves the purpose of storage and showcase with the ease of access for both students and evaluators. The knowledge and skills regarding immunization in medical students are of utmost importance for the successful implementation and conduction of the Universal Immunization Program in the country.

Systolic Anterior Motion of the Mitral Valve Post-Heart Transplant Secondary to an Unusual Mechanism.

In this case report, we discuss the critical interdependence of structure and function in demonstrating systolic anterior motion (SAM) of the mitral valve after repeat heart transplantation, where residual apical tissue of the explanted heart remained in place. The resulting conformational changes led to anterior displacement of the mitral valve and persistent SAM.

Forecasting demand data for critical materials.

Gallium, Indium and Cobalt are critical materials that are vital to ramping up the adoption of clean energy technologies such as solar photovoltaics (PVs), electric vehicles (EVs) and wind turbines (WTs). Like other critical materials, they are prone to supply chain risks resulting in future uncertainty associated with supply, demand and price parameters. Understanding current and future market dynamics will mitigate this uncertainty.

Comparison of amount of noise and elimination strategies for noise in neonatal intensive care units of government and private hospitals in the Jodhpur district of India.

With technological advancement, neonatal intensive care units (NICUs) have become noisier than ever. Studies have shown the detrimental effects of increasing noise in NICU on growing pre-term and sick neonates. The present study aimed primarily to compare the amount of noise in NICUs of private and government hospitals.

Evaluation of Neuroprotective Effect of Gut Microbe in Parkinson's Disease: An In Silico and In Vivo Approach.

Parkinson's disease is a progressive neurodegenerative disorder marked by the death of dopaminergic neurons in the substantia nigra region of the brain. Aggregation of alpha-synuclein (α-synuclein) is a contributing factor to Parkinson's disease pathogenesis. The objective of this study is to investigate the neuroprotective effects of gut microbes on α-synuclein aggregation using both in silico and in vivo approaches.

COVID-19 Stigma and Discrimination in a North Indian State: A Concurrent Mixed Method Study.

We measured COVID-19-related stigma and discrimination and its drivers using a concurrent mixed-methods design in Punjab. The simple random sampling was used to select blocks, subcenters, and urban primary healthcenters from each of the four selected districts. The systematic random sampling was used to select households.

Bound Isoscalar Axial-Vector bcu[over ¯]d[over ¯] Tetraquark T_{bc} from Lattice QCD Using Two-Meson and Diquark-Antidiquark Variational Basis.

We report a lattice QCD study of the heavy-light meson-meson interactions with an explicitly exotic flavor content bcu[over ¯]d[over ¯], isospin I=0, and axial-vector J^{P}=1^{+} quantum numbers in search of possible tetraquark bound states. The calculation is performed at four values of lattice spacing, ranging from ∼0.058 to ∼0.

Correlation of non-invasive parameters with upper gastrointestinal endoscopy findings for presence and grading of gastroesophageal varices in liver cirrhosis patients.

Background: Development of esophageal varices is one of the major complications of liver cirrhosis, and endoscopy is used to see the presence, grading, and long-term monitoring of esophageal varices which is an invasive and unpleasant procedure. There is no adequate data available showing noninvasive methods can be used for the same.

Methods: Seventy patients with liver cirrhosis participated in the study.

A Review on Indole-triazole Molecular Hybrids as a Leading Edge in Drug Discovery: Current Landscape and Future Perspectives.

Molecular hybridization is a rational design strategy used to create new ligands or prototypes by identifying and combining specific pharmacophoric subunits from the molecular structures of two or more known bioactive derivatives. Molecular hybridization is a valuable technique in drug discovery, enabling the modulation of unwanted side effects and the creation of potential dual-acting drugs that combine the effects of multiple therapeutic agents. Indole-triazole conjugates have emerged as promising candidates for new drug development.

A teleradiology network for the improvement of healthcare and patient management in the developing countries of the African continent.

Introduction: Africa is the second-largest continent on Earth in terms of both size and population. However, inaccessibility and shortfall of trained radiologists impede the delivery of adequate healthcare to such a large population. Teleradiology holds considerable potential in improving patient outcomes and healthcare delivery in African nations by furnishing timely interpretation of radiological examinations, particularly in those areas where there is a particular scarcity of radiologists.

Cine Medicine in Indian Scenario: A SWOT Analysis.

Cinema has the ability to convey important messages in an engaging and interesting manner. Cine medicine also known as cinema medicine or Cinemeducation has the potential to teach medical students and healthcare professionals about various aspects of medical conditions and illnesses. It is an innovative approach that can enhance empathy among the students and understanding toward patients with various medical conditions.

Catastrophic impact of 1947 partition of India on people's health.

Introduction: The partition of India on the dissolution of British Raj into two dominions is known to have been violent, polarizing and caused large-scale loss of life (about two million) and an unprecedented migration of 14 million people between the two dominions, India and Pakistan. It is not known how well the then scientific community covered this man-made disaster, and the response of the international community with aid.

Methodology: A systematic review was conducted using different electronic databases of PubMed, Econlit, United Nations resolutions, Government of India websites, and Google Scholar for the period January 1947 to December 1951 on the impact of the partition of the Indian sub-continent, and to identify the international response toward this humanitarian crisis.

Highly reversible extrinsic electrocaloric effects over a wide temperature range in epitaxially strained SrTiO films.

Electrocaloric effects have been experimentally studied in ferroelectrics and incipient ferroelectrics, but not incipient ferroelectrics driven ferroelectric using strain. Here we use optimally oriented interdigitated surface electrodes to investigate extrinsic electrocaloric effects in low-loss epitaxial SrTiO films near the broad second-order 243 K ferroelectric phase transition created by biaxial in-plane coherent tensile strain from DyScO substrates. Our extrinsic electrocaloric effects are an order of magnitude larger than the corresponding effects in bulk SrTiO over a wide range of temperatures including room temperature, and unlike electrocaloric effects associated with first-order transitions they are highly reversible in unipolar applied fields.

Utilization of Teleradiology by Intensive Care Units: A Cohort Study.

Aim And Background: Imaging is indispensable to the diagnostic and treatment process. By facilitating access to rapid timely image interpretation, teleradiology plays a prominent role in improving access, quality of critical care, and management of the patients in intensive care units (ICU). The aim of the study is to investigate the role of teleradiology in ICU patient care and management.

Synthesis, Molecular Docking, and Biological Evaluation of Novel Indole-triazole Conjugates.

Background: Indole-triazole conjugates have emerged as promising candidates for new drug development. Their distinctive structural characteristics, coupled with a wide array of biological activities, render them a captivating and promising field of research for the creation of novel pharmaceutical agents.

Objective: This study aimed to synthesize indole-triazole conjugates to investigate the influence of various substituents on the functional characteristics of indole-triazole hybrids.

Development of Alpha-Synuclein protein model against therapeutic aspects of Parkinson's disease.

JOURNAL/ijpha/04.03/01363791-202456010-00007/figure1/v/2024-03-07T095025Z/r/image-tiff Parkinson's disease (PD) is the most common neurodegenerative disease caused by the steady depletion of dopamine in the striatum due to the loss of dopaminergic neurons. Most of the current therapeutics work on rebuilding the striatal dopamine level through oral administration of levodopa which stops the symptoms of PD.

Outcomes of Central Neck Dissection for Papillary Thyroid Carcinoma in Primary Versus Revision Setting.

Introduction: Surgery in the central compartment after previous thyroidectomy involves an increased risk of injury to critical organs, including the parathyroids and recurrent laryngeal nerve. Contrastingly, primary central neck dissection involves a relatively low operative risk.

Objective: This study aimed to compare the outcomes of central neck dissection in primary versus revision settings with respect to the lymph node yield and complication rates.

Laparoscopic Management of Auto-Amputated Ovarian Cyst in an Infant.

The routine schedule of antenatal ultrasound scans has led to an increased frequency of detection of foetal ovarian cysts. Although most of them regress spontaneously, some may grow into large cysts and undergo torsion followed by auto-amputation. However, pre- and post-natal scans may fail to identify this event.

Chemical exfoliation of 1-dimensional antiferromagnetic nanoribbons from a non-van der Waals material.

As the demand for increasingly varied types of 1-dimensional (1D) materials grows, there is a greater need for new methods to synthesize these types of materials in a simple and scalable way. Chemical exfoliation is commonly used to make 2-dimensional (2D) materials, often in a way that is both straightforward and suitable for making larger quantities, yet this method has thus far been underutilized for synthesizing 1D materials. In the few instances when chemical exfoliation has been used to make 1D materials, the starting compound has been a van der Waals material, thus excluding any structures without these weak bonds inherently present.

Force-induced unzipping of DNA in the presence of solvent molecules.

The melting of double-stranded DNA (dsDNA) in the presence of solvent molecules is a fundamental process with significant implications for understanding the thermal and mechanical behavior of DNA and its interactions with the surrounding environment. The solvents play an essential role in the structural transformation of DNA subjected to a pulling force. In this study, we simulate the thermal and force induced denaturation of dsDNA and elucidate the solvent dependent melting behavior, identifying key factors that influence the stability of DNA melting in presence of solvent molecules.

Socioeconomic Impact on Swallow Therapy Attendance.

Dysphagia negatively impacts quality of life and increases health care costs. Swallow therapy is the primary and effective treatment for dysphagia of various etiologies, and attendance is critical to success. This study seeks to identify barriers to swallow therapy attendance at a tertiary care, safety-net hospital.