Retroperitoneal fibrosis. A follow-up study.

13 patients with retroperitoneal fibrosis (RPF) were reviewed. 10 patients had idiopathic disease and in 3 patients the disease was secondary to temporal arteritis, aortic aneurysm and ergotamine ingestion. Ureterolysis was performed in all patients.

Diagnosis of hyperparathyroidism in patients with urolithiasis using measurement of serum immunoreactive parathyroid hormone and serum calcium.

Serum immunoreactive PTH (iPTH) was measured in 74 patients with urolithiasis and correlated to the corresponding serum calcium values. Serum iPTH was measured using a rooster antibovine iPTH antiserum which crossreacted with the human hormone within the 44-68 amino acid residue region. Sixty-six of these patients had normal serum iPTH and calcium concentrations.

Sigmoidocystoplasty in adults with enuresis.

Sigmoidocystoplasty was performed upon 13 adult patients with enuresis to increase the small bladder capacity. Eleven patients were in the follow-up study. The mean observation time was 29.

Total replacement of the ureter with a segment of ileum. A follow-up study.

Total replacement of the ureter with a segment of ileum was performed on seven patients. Five of them were followed up for a mean of 20 months. The results of the operation were good.

Sigmoidocystoplasty: a follow-up study.

Sigmoidocystoplasty was performed in 62 patients. 36 were followed up. The mean observation period was 68 months, ranging from 6 to 318 months.

Endocrine tumors of the pancreas.

A review of 33 patients operated on between 1951 and 1978 for endocrine tumors of the pancreas is presented. The series consists of 25 patients with hyperinsulinism, 6 with the Zollinger-Ellison syndrome, and 2 with the WDHA syndrome. Clinical features and diagnostic problems are discussed.

Probable endometrial carcinoma of the prostate, crossed renal ectopia and dermatomyositis in a 32-year-old man.

An unusual type of prostatic carcinoma associated with crossed renal ectopia and dermatomyositis is reported in a young man. Infiltration by an epithelial tumor filled the enlarged prostate with soft papillary masses. Cystoprostatectomy and removal of a single large pelvic lymph node metastasis were done.

Recto-urethral fistula. Treatment by abdomino-perineal pull-through resection of the rectum.

4 patients with difficult and longlasting recto-urethral fistulas were treated by abdominoperineal pull-through resection of the rectum. Primary closure of the fistula occurred in all cases. We suggest that this operative technique should be taken into consideration in cases of difficult rectourthral fistulas.

Air cystometry at different flow rates.

Air cystometry was performed with 3 different flow rates in patients suffering from different bladder diseases. To demonstrate neurogenic bladder disorder a flow rate of 75 ml/min was recommended.

A test of the sympathic nervous system of the urethra.

The administration of 5 mg phentolamine by a new technique decreases the urethral closure pressure by 38%. The latter could be used as a test for the sympatic nervous system in the urethra.

Total replacement of ureter with a segment of ileum.

Replacement of ureter with a segment of ileum was successfully performed in two patients. One had ureteral cancer and the other recurrent calculi due to cystinuria. The first patient had only one kidney.

Metabolism of testosterone in the human prostate and seminal vesicles.

Tissue from the normal, hyperplastic and the cancerous human prostate as well as tissue from the human seminal vesicles are capable of metabolizing testosterone in vitro. By incubating minced tissue with 3H-testosterone for 2 hours at 37 degrees C the following radioactive metabolites were identified: testosterone (17 beta-hydroxyl-4-androsten-3-one), androstenedione (4-androstene-3,17-dione), androstanedione (5alpha-androstane-3,17-dione), 5alpha-dihydrostestosterone (17 beta-hydroxy-5alpha-androstane-3-one, DHT), 3alpha-androstanediol (5alpha-androstane-3alpha,17beta-diol), 3beta-androstanediol (5alpha-androstane-3beta-17beta-diol) and androsterone (3alpha-hydroxy-5alpha-androstane-17-one). When normal human prostatic tissue was incubated with 3H-testosterone approximately 40% of the hormone was metabolized and 30-35% of the metabolites were identified as DHT.

Duplication of the male urethra treated by septotomy. A case report.

In a case of incomplete duplication of the male urethra the interurethral septum was divided by scissors. After this simple operative procedure, the patient was relieved of his obstructive symptoms. Postoperative urethrography revealed considerable improvement of the calibre of the urethral lumen, and uroflowmetry showed almost normalized flow values.

Uretero-vaginal fistula.

Six cases of uretero-vaginal fistula are presented. Five patients developed this complication after gynaecological surgery and one after Caesarian section. Constant urinary incontinence combined with normal voiding is typical of this lesion.