Bootstrapping the visuospatial bootstrapping effect and testing its spatialisation.

When sequences of digits are visually presented within a numerical keypad on a screen, memory span increases, this effect was named visuospatial bootstrapping. The aim of the first experiment was to know if this effect could emerge without presenting a keypad on the screen. For this purpose, a three-phase experiment was designed.

Western diet, obesity and bariatric surgery sequentially modulated anxiety, eating patterns and brain responses to sucrose in adult Yucatan minipigs.

Palatable sweet/fatty foods overconsumption is a major risk factor for obesity and eating disorders, also having an impact on neuro-behavioural hedonic and cognitive components comparable to what is described for substance abuse. We hypothesized that Yucatan minipigs would show hedonic, cognitive, and affective neuro-behavioral shifts when subjected to western diet (WD) exposure without weight gain, after the onset of obesity, and finally after weight loss induced by caloric restriction with (RYGB) or without (Sham) gastric bypass. Eating behavior, cognitive and affective abilities were assessed with a spatial discrimination task (holeboard test) and two-choice feed tests.