Publications by authors named "Mathilde Legrix"

Article Synopsis
  • * The H1047R mutation is linked to developmental issues including macrocephaly and cleft palates, particularly affecting neuroectodermal derivatives and causing vascular anomalies associated with neural crest-derived tissues.
  • * By studying mouse models, researchers found new lineages that could contribute to disease development and observed that certain cell types, like Schwann cell precursors, show a connection to vascular tumors when activated, offering insights into potential human PIK
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Antipsychotic treatment can produce a dopamine-supersensitive state, potentiating the response to dopamine receptor stimulation. In both schizophrenia patients and rats, this is linked to tolerance to ongoing antipsychotic treatment. In rodents, dopamine supersensitivity is often confirmed by an exaggerated psychomotor response to d-amphetamine after discontinuation of antipsychotic exposure.

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