Publications by authors named "Mathilde Lambert"
Introduction: Health inequalities represent a major challenge in contemporary medicine, with some attributed to racial biases. Recently, in the United States, a call to combat discrimination in the field of health has resonated, particularly in the context of the COVID-19 crisis, in which minorities have been disproportionately affected. These calls echo recommendations from the Institute of Medicine dating back to 2001, urging the fight against inequalities in access to health care.
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- The study investigates the presence and importance of autoantibodies against lysobisphosphatidic acid (aLBPA) in patients with antiphospholipid syndrome (APS).
- It compares 91 patients with antiphospholipid antibodies—60 symptomatic and 31 asymptomatic—to 33 controls, finding a higher prevalence of aLBPA among patients.
- The research suggests that testing for aLBPA alongside conventional antiphospholipid antibodies may help in managing APS, especially in deciding if asymptomatic patients should receive preventive treatment.
Objectives: This review aims to identify biological markers associated with the risk of recurrence of thrombotic and/or obstetric events in patients with antiphospholipid syndrome (APS).
Methods: A comprehensive review of literature was conducted to evaluate established and potential novel biological markers associated with thrombosis in APS. To this end, a PubMed literature search was conducted for the last twenty years using the following keywords or their combinations: thrombotic risk, recurrence of thrombosis, risk stratification, severity, predictive value.
Background: Although the triple positivity of antiphospholipid antibodies (aPL) is important for classifying high-risk patients, interpretation of aPL positivity, namely the lupus anticoagulant (LA), anti-cardiolipin (aCL), and anti-beta2-glycoprotein I autoantibodies (aB2GPI) remains challenging for thrombotic risk stratification.
Objective: To compare biological and clinical data between triple aPL- and single aCL-positive patients.
Methods: Of the 6500 patients assayed for aPL in daily practice within 3 years, we retrospectively analyzed data from 161 patients that were either triple aPL-positive or single aCL-positive with 5 years' follow-up for 121 of them.
Objective: Postpartum Depression (PPD) affects over 15% new mothers. Its etiology is multifactorial and still partly unknown. Some hypotheses suggest a link with inflammation.
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