In malaria-endemic regions, and coexist and may interact. For instance, fevers induced by might activate dormant parasites and concurrent radical cure of both species has been proposed to prevent relapses. Heterogeneous mosquito exposure may contribute to the dependence of both parasites.
View Article and Find Full Text PDFWe present an approach to extend the endemic-epidemic (EE) modelling framework for the analysis of infectious disease data. In its spatiotemporal formulation, spatial dependencies have originally been captured by static neighbourhood matrices. These weight matrices are adjusted over time to reflect changes in spatial connectivity between geographical units.
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