Publications by authors named "Mathilde Gaillard"
Article Synopsis
- Mature blood cells develop from hematopoietic stem cells in bone marrow through a differentiation process that may be either organized (instructive) or random (stochastic).
- Research using single-cell transcriptomic data showed variability in gene expression during blood cell differentiation, with notable peaks in variability at certain stages across different cell lineages.
- Findings suggest that hematopoietic differentiation should be viewed as a dynamic stochastic process characterized by periods of uncertainty, supporting the idea that differentiation involves significant cell-to-cell variability.
