Publications by authors named "Mathilde Bouchereau"

Article Synopsis
  • Early empirical antimicrobial treatment is common for critically ill COVID-19 patients, and this study looked at how often bacteria were identified in patients with SARS-CoV-2 pneumonia versus those with influenza pneumonia.
  • In a study involving 1,050 patients across 36 ICUs, only 9.7% of SARS-CoV-2 patients had bacterial infections identified within the first 48 hours after intubation compared to 33.6% in influenza patients.
  • Coinfections in both groups were primarily caused by gram-positive cocci, and while bacterial identification increased the risk of 28-day mortality for SARS-CoV-2 patients, the overall impact on mortality was similar for both conditions.
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Background: Patients with SARS-CoV-2 infection are at higher risk for ventilator-associated pneumonia (VAP). No study has evaluated the relationship between VAP and mortality in this population, or compared this relationship between SARS-CoV-2 patients and other populations. The main objective of our study was to determine the relationship between VAP and mortality in SARS-CoV-2 patients.

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Purpose: Although patients with SARS-CoV-2 infection have several risk factors for ventilator-associated lower respiratory tract infections (VA-LRTI), the reported incidence of hospital-acquired infections is low. We aimed to determine the relationship between SARS-CoV-2 pneumonia, as compared to influenza pneumonia or no viral infection, and the incidence of VA-LRTI.

Methods: Multicenter retrospective European cohort performed in 36 ICUs.

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