Photodynamic therapy as novel nephron sparing treatment option for small renal masses.

Purpose: Photodynamic therapy has great potential as nephron sparing therapy for small renal masses. Using mTHPC [meso-tetra(hydroxyphenyl)chlorin] (BioLitec Pharma, Dublin, Ireland), a photosensitizer that targets vasculature and tissue, we determined whether renal tumors could be ablated using mTHPC mediated photodynamic therapy in a translational renal carcinoma mouse model.

Materials And Methods: We administered mTHPC intravenously in kidney tumor bearing mice.