Publications by authors named "Mathieu S Chevalier"
Page 1 of 1
Synopsis of recent research by authors named "Mathieu S Chevalier"
- Mathieu S Chevalier's research primarily focuses on the interactions between human cytomegalovirus (HCMV) proteins and major histocompatibility complex (MHC) molecules, particularly in the context of viral evasion of the immune system.
- His studies reveal that specific HCMV proteins, like US2 and US11, facilitate the degradation of MHC class I and II proteins through interactions with the cellular endoplasmic reticulum-associated degradation machinery, including the chaperone BiP.
- Chevalier's findings highlight the mechanism by which HCMV manipulates MHC protein degradation, illustrating how viral proteins exploit normal cellular processes to impair antigen presentation and evade immune detection.
