Publications by authors named "Mathieu Robichaud"
Article Synopsis
- The study aimed to explore outcomes of transcatheter patent foramen ovale (PFO) closure in patients over 60 years old, particularly looking at recurrent cerebrovascular events (CVE) and atrial fibrillation (AF).
- Involving 689 patients, the procedural success rate was high at 99.4%, but there were notable risks: 9.6% of patients died during follow-up, and diabetes and atrial septal aneurysm were linked to increased CVE events.
- The findings suggest that while most older patients experience low rates of CVE and AF post-procedure, factors like diabetes, atrial septal aneurysms, and increasing age are important in guiding clinical decisions regarding PFO closure.
Article Synopsis
- A study was conducted to evaluate the clinical outcomes and quality of life (QoL) among patients aged 90 and older after undergoing transcatheter aortic valve replacement (TAVR) from 2008 to 2020.
- The results showed that TAVR patients had a better survival rate compared to those receiving medical therapy, with significant improvements in functional status and various QoL metrics up to one year post-procedure.
- Overall, nonagenarians who underwent TAVR experienced improved survival and enhanced quality of life compared to their peers in the general population.
Patent foramen ovale (PFO) closure, along with medical therapy, has emerged as the therapeutic gold standard in younger (<60-year-old) patients with a PFO-related stroke for preventing recurrent events. However, PFO management guidelines lack definite recommendations for older (>60 years) patients with a PFO-related cerebrovascular event, a complex group of patients who were mostly excluded from PFO closure clinical trials. Nevertheless, several studies have shown a higher prevalence of PFO among older patients with cryptogenic stroke, and its presence has been associated with an increased risk of recurrent events.
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- A study investigated sex differences in patients with cryptogenic cerebrovascular events undergoing patent foramen ovale (PFO) closure, analyzing data from 1,076 patients over an average follow-up period of 3 years.
- Results showed women were generally younger than men and had a higher risk of paradoxical embolism, although procedural characteristics were similar across genders.
- At follow-up, while stroke rates were not significantly different, women experienced a higher incidence of combined ischemic cerebrovascular events and bleeding complications compared to men.
Background: The updated Valve Academic Research Consortium (VARC) definition for bleeding events after transcatheter aortic valve replacement (TAVR) lacks of clinical validation.
Objectives: The aim of this study was to determine the incidence, predictors, and clinical impact of bleeding events following TAVR as defined by recent VARC-3 criteria.
Methods: A total of 2,384 consecutive patients with severe symptomatic aortic stenosis undergoing TAVR were included.
Limited data exist on patients with a transient ischemic attack (TIA) who underwent patent foramen ovale (PFO) closure. The objectives of this study were to determine the clinical and procedural characteristics and long-term outcomes of patients with TIA who underwent transcatheter PFO closure. This was a multicenter study including 1,012 consecutive patients who underwent PFO closure after a cerebrovascular event.
View Article and Find Full Text PDFBackground: High (≥20 mmHg) postprocedural mean transvalvular gradients are relatively common among valve-in-valve (ViV) transcatheter aortic valve replacement (TAVR) recipients, but its clinical impact remains controversial.
Methods: Observational study including 190 consecutive ViV-TAVR recipients. Patients were classified according to the presence of high (≥20 mmHg) or low (<20 mmHg) residual mean transvalvular gradient on post-procedural echocardiography.