Birth Weight Is Associated With the IGF-1 Response to GH in Children: Programming of the Anabolic Action of GH?

Context: Intrauterine programming of the somatotropic axis has been hypothesized in cases of intrauterine growth retardation.

Objective: The objective of the study was to study the effects of birth weight and body composition on GH sensitivity.

Design: This was a cross-sectional study with a single GH administration to assess GH sensitivity.