Publications by authors named "Mathieu Ballouche"
Article Synopsis
- * The small RNA SraG is positioned between the rpsO and pnp genes and is transcribed oppositely; while its function was previously unknown, it has been shown to affect pnp expression.
- * Overexpressing SraG decreases pnp levels and destabilizes its mRNA, while inhibiting SraG increases pnp expression, suggesting that SraG directly regulates pnp through antisense interactions.
Iron metabolism: a promising target for antibacterial strategies.
Recent Pat Antiinfect Drug Discov
November 2009
In the fight against pathogenic and opportunistic bacteria, development and spreading of resistance to antibiotics is an increasing public health problem. The available antibacterial treatments are becoming less and less effective, making urgent the discovery of new active molecules. One strategy that has been explored to bypass the bacterial adaptation to drugs is to target the iron metabolism of bacteria, since iron is critical for all bacteria to grow.
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