Publications by authors named "Mathias Walter Hornef"
Article Synopsis
- Early-life immune development is essential for long-term health, but the factors influencing postnatal immune maturation are not well understood.
- The study focused on mononuclear phagocytes in Peyer's patches, showing significant age-related changes that led to reduced T cell priming in young organisms.
- The research identified that the differentiation of follicle-associated epithelium M cells is crucial for driving the maturation of these immune cells after weaning.
Background & Aims: Growing evidence supports a role of gut-derived metabolites in nonalcoholic fatty liver disease (NAFLD), but the relation of endotoxin levels with gut permeability and NAFLD stage remains unclear. This systematic review with meta-analysis aims to provide further insights.
Methods: PubMed, Embase, and Cochrane Library were searched for studies published until January 2022 assessing blood endotoxins in patients with NAFLD.
Abdominal infections including cholangitis represent a major problem in patients with perihilar cholangiocarcinoma (pCCA). Thus, we investigated bacterial colonization of the bile ducts and determined its impact on postoperative outcome focusing on abdominal infections. A cohort of 95 pCCA patients who underwent surgery between 2010 and 2019 with available intraoperative microbial bile cultures were analyzed regarding bile duct colonization and postoperative abdominal infection by group comparisons and logistic regressions.
View Article and Find Full Text PDFHere we report the first human case of an outer ear canal infection with a free-living nematode of the genus Rhabditis. Otomicroscopy revealed viable worms in the outer ear canal of a patient suffering from chronic otorrhea and hearing loss. The nematode was identified by microscopy and internal transcribed spacer (ITS)-PCR.
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