Publications by authors named "Mathias Reiersen"
J Biomed Mater Res A
July 2022
Article Synopsis
- The foreign body response significantly influences wound healing around implanted materials, especially in patients with chronic inflammatory conditions, leading to a higher risk of implant failure.
- The study evaluated the effects of surface coatings made from antioxidant polyphenolic molecules, tannic acid (TA) and pyrogallol (PG), on the host response in human blood and found that these coatings improved initial blood protein interactions and hemocompatibility with titanium surfaces.
- Although the coatings reduced reactive oxygen species in fibroblasts, they did not exhibit strong anti-inflammatory effects, as certain inflammatory pathways remained activated despite the presence of the polyphenolic coatings.
