Correlation between insulin resistance and liver histology in patients with nonalcoholic steatohepatitis with and without obesity.

Introduction: Insulin resistance (IR) plays a central role in pathogenesis of nonalcoholic steatohepatitis (NASH). The aim of this study was to correlate histopathological grading and IR in overweight/obese patients with NASH as compared with lean NASH.

Methods: Patients with NASH who underwent liver biopsy between January 2012 and December 2012 were included.