Publications by authors named "Mathew Breen"
J Cell Mol Med
August 2017
Article Synopsis
- Cardiosphere-derived cells (CDCs) have shown potential in reducing scar tissue and enhancing heart muscle viability in patients with myocardial infarction, and preliminary studies suggest benefits in non-ischaemic dilated cardiomyopathy (DCM).
- In a study using a canine model, researchers infused 30 million allogeneic CDCs from a donor dog into Doberman pinschers affected by spontaneous DCM.
- The infusion process was safe, with no adverse events observed, and subsequent heart tissue analysis indicated no signs of immune rejection of the transplanted cells.
