Effects of valproic acid on wound healing of the abdominal wall musculoaponeurotic layer: an experimental study in rats.

Introduction: valproic acid (VPA), an epigenetic drug, has potential for the treatment of neoplasms. Its effects on the healing of the peritoneal-musculo-aponeurotic plane (PMA) of the abdominal wall are studied.

Method: sixty Wistar rats were allocated into two groups: experimental (VPA) and control (0.

Valproic acid and bladder healing: an experimental study in rats.

Purpose: to recognize the effects of valproic acid (VPA), an epigenetic drug, on the bladder healing process, in rats.

Method: twenty male Wistar rats were divided in two groups: experimental (A), treated with VPA (150mg/Kg/day), and control (B) with 0.9% sodium chloridrate.