Shared Binding Mode of Perrottetinene and Tetrahydrocannabinol Diastereomers inside the CB1 Receptor May Incentivize Novel Medicinal Drug Design: Findings from an Assay.

In recent years, therapeutic compounds derived from phytocannabinoids have brought renewed attention to the benefits they offer to ameliorate chronic disease symptoms. Among cannabinoids, tetrahydrocannabinol (THC) is a well-known component of the plant, whose active principles have been studied through the years. Another psychoactive phytocannabinoid, derived from liverworts , perrottetinene (PET), has created interest, especially as a pharmaceutical product and for its legal recreational use.