Design, Development and Validation of a Customised Mind-Body Module Towards Resilience Building and Wellness Promotion.

In today's world, developing resilience is crucial for managing stress, preserving mental and emotional health, managing work-life balance, fostering self-growth and good relationships and promoting physical health. Nourishing the mind-body connection, using methods for stress reduction and self-care and incorporating a Mind Body Module can contribute to resilience-building initiatives as well as help in wellness promotion. This study aims to design, develop and validate a resilience-building module that incorporates mind-body practices.

Barriers to Voice Therapy: A Report From Beginners, Performers, and Teachers of Carnatic Music.

Aim: The study aimed to understand awareness, perceptions, and barriers to voice therapy among beginners, performers, and teachers of Carnatic music.

Method: Barriers from the literature were obtained, and the guide for the semistructured interview was developed. Twelve Carnatic singers (four each identified as beginners, performers, and teachers) were contacted and interviewed on an online platform.

Effect of LED photobiomodulation on fluorescent light induced changes in cellular ATPases and Cytochrome c oxidase activity in Wistar rat.

Background: Fluorescent light exposure at night alters cellular enzyme activities resulting in health defects. Studies have demonstrated that light emitting diode photobiomodulation enhances cellular enzyme activities.

Objective: The objectives of this study are to evaluate the effects of fluorescent light induced changes in cellular enzymes and to assess the protective role of pre exposure to 670 nm LED in rat model.

Predictive value of craniofacial and anthropometric measures in obstructive sleep apnea (OSA).

Background: Most individuals with OSA remain undiagnosed, mainly due to limited access to effective screening tools and diagnostic facilities. Therefore, the objective of this study was to identify craniofacial and anthropometric measurements that predict OSA in an Indian population.

Methods And Findings: Male subjects (n = 76) between 25 and 50 years of age were recruited for the study from the general population.

Second digit and fourth digit ratio--an adjunct tool to predict obstructive sleep apnea.

Obstructive sleep apnea (OSA) is a sleep related breathing disorder associated with high morbidity and mortality. Digit ratio (2D:4D) a sexually dimorphic trait is a putative indicator of prenatal testosterone exposure and adult testosterone level. Present study aimed at investigating the correlation between 2D:4D ratio and OSA based on the study conducted on 290 volunteered participants of both the sexes in the age range of 20-45 years.

Protective effect of light emitting diode phototherapy on fluorescent light induced retinal damage in Wistar strain albino rats.

Background: Artificial light at night alters retinal physiology. Several studies have shown that light emitting diode phototherapy protects the retina from the damaging effects of acute light exposure.

Objective: The aim of this study has been to elucidate the protective effects of 670 nm LED light on retinal damage induced by chronic fluorescent light in Wistar rats.

Changes in maternal lipid peroxidation before and immediately after delivery.

Oxidative damage has been implicated in pathogenesis of many diseases. It is known that various kinds of stresses accelerate the production of free radicals. As pregnancy being a physiological state accompanied by a high energy demand of many bodily functions and an increased oxygen requirement, increased level of oxidative stress would be expected.

Effect of REM sleep deprivation on the antioxidant status in the brain of Wistar rats.

Background: Rapid eye movement [REM] sleep deprivation is a stressor. It results in a predictable syndrome of physiological changes in rats. It has been proposed that reactive oxygen species and the resulting oxidative stress may be responsible for some of the effects of sleep deprivation.

Behavioral analysis after sciatic nerve compression in albino rats.

Background: Walking track analysis which has been widely used to examine the recovery of gait functions in rats with sciatic nerve injury.

Purpose: The present study was aimed to objectively analyze and quantify the degree of functional recovery in locomotor behavior of rats after inflicting sciatic nerve crush injury.

Methods: Wistar rats trained on various runways, viz.

Effect of alpha-ketoglutarate on neurobehavioral, neurochemical and oxidative changes caused by sub-chronic cyanide poisoning in rats.

Recent studies revealed that alpha-ketoglutarate (A-KG) alone or with sodium thiosulfate (STS) provide significant protection against acute and sub-acute cyanide poisoning in rodents. This study addresses the protective effect of A-KG and/or STS in sub-chronic (90 days) cyanide poisoning. Wistar rats were divided into seven groups (n = 10): Control animals, potassium cyanide (KCN) A-KG, STS, KCN + A-KG, KCN + STS and KCN + A-KG + STS.

Neurochemical and behavioural correlates in cassava-induced neurotoxicity in rats.

Chronic cyanide intoxication from cassava has been implicated as the cause for a degenerative neuropathy known widely as tropical ataxic neuropathy. An attempt has been made in this study to identify the specific cause for neuropathy caused by cassava using Wistar strain albino rats as the experimental animal model. The results of cassava fed animals were compared with control animals, animals given cyanide, malnourished animals and malnourished animals fed cyanide, to identify the causative factors.

Free radical changes in methanol toxicity.

Role of free radicals in methanol toxicity was evaluated in methanol treated albino rats. Methanol intoxication increased lipid peroxidation and depleted the free radical scavenging enzyme systems. The free radical quenching effect of vitamin E protected the animals from methanol induced free radical damage.

Protective effect of diltiazem on cyanide-induced neurotoxicity in Wistar strain rats.

Cyanide is a well-established poison known for its rapid lethal action and toxicity. The central nervous system is one of the main target sites for cyanide toxicity. Cyanide not only alters brain biogenic amine levels but also the intracellular calcium levels in the neuronal cells.

Calcium ions: its role in cyanide neurotoxicity.

Cyanide is a well-established poison known for its rapid lethal action and toxicity. The central nervous system is one of the main target sites for cyanide toxicity. Cyanide also alters the brain biogenic amine levels.

Effect of chronic protein restriction on motor co-ordination and brain neurotransmitters in albino rats.

In this study we evaluated the motor co-ordination in Wistar strain albino rats that were maintained on a protein-restricted diet for a period of 1 year immediately after the weaning period, by substituting 75% of the normal diet with a carbohydrate-rich diet deficient in protein, for a period of 1 year immediately after the weaning period. This type of chronic protein restriction caused disturbances in motor co-ordination. It also caused a significant reduction in the basal levels of dopamine, norepinephrine, epinephrine and serotonin along with their metabolites homovanillic acid (HVA), vanillyl mandelic acid (VMA) and 5-hydroxy indoleacetic acid (5HIAA) and precursor L-dopa in the corpus striatum and cerebellum.

Effect of cassava consumption on open-field behavior and brain neurotransmitters in albino rats.

Diet exerts a critical influence on human biology and thus studies on the interrelationship of nutrition and behavior continues to be a major and important focus of research in the natural experimental sciences. Cassava is known to cause metabolic and neurological derangement on long-term consumption as a staple diet in the tropics. In this article we present the effects of cassava consumption on open-field behavior and catecholamine levels in the hypothalamus of albino rats.

Long-term ingestion of cassava (tapioca) does not produce diabetes or pancreatitis in the rat model.

Cassava (tapioca, manihot) is consumed as a staple food in some developing countries. The intake of cassava has been linked to several diseases including fibrocalculous pancreatic diabetes (tropical calcific pancreatitis). There are few long-term studies on the effect of cassava ingestion on the pancreas in animal models.

Effect of chronic cyanide intoxication on memory in albino rats.

Cyanide is a chemical widely used in industry, and is a major environmental pollutant. Its toxicity is caused by inhibition of cytochrome oxidase resulting in histotoxic hypoxia. The effect of sublethal doses of cyanide on memory and hippocampal neurotransmitters was studied in male Wistar strain albino rats.

Effect of Cassava on motor co-ordination and neurotransmitter level in the albino rat.

The root of Cassava, a tropical plant, is consumed in the tropics and has been attributed as the cause for various tropical neuropathies. This study aims to discover the neurotoxic effects of chronic cassava consumption of Indian origin and the effect of malnutrition. The assessment is based on the motor co-ordination and brain neurotransmitters in rats.

Activated charcoal--an antidote to methyl alcohol poisoning.

Every year a considerable number of people die due to methly alcohol poisoning, in which most of them die even before they are given proper treatment. This report gives a simple and cheap first aid measure to those affected by methanol poisoning by the administration of activated charcoal. This study has shown that the mortality of methanol recipient rats have significantly reduced by the administration of activated charcoal.