Innate lymphoid cells and tumor-derived lactic acid: novel contenders in an enduring game.

Aerobic glycolysis, also known as the Warburg effect, has for a prolonged period of time been perceived as a defining feature of tumor metabolism. The redirection of glucose utilization towards increased production of lactate by cancer cells enables their rapid proliferation, unceasing growth, and longevity. At the same time, it serves as a significant contributor to acidification of the tumor microenvironment, which, in turn, imposes substantial constraints on infiltrating immune cells.

The Psychological Well-Being and Civic Engagement of Polish, Croatian and Lithuanian Academic Students during COVID-19 Outbreak.

The aim of this research was to recognize the relationship between well-being and civic engagement under the difficult circumstances of the COVID-19 pandemic amongst students from Poland, Lithuania and Croatia. Overall, 1362 academic students (Poland, n = 596, Croatia, n = 386, and Lithuania, n = 379) participated in the study. Mean rank differences in civic engagement level (overall CE) were analysed by levels of psychological well-being (overall PWB and its subscales) using the Kruskal-Wallis test (one-way ANOVA on ranks).

Assessment of Physical Well-Being and Leisure Time of Polish Students during the COVID-19 Outbreak.

This project aims to recognize the school experiences of Polish students during the COVID-19 outbreak; we focused on the area of assessment of physical well-being and leisure time. Nearly two thousand primary or secondary school students aged 9 to 20 participated in the survey. Running descriptive statistics, frequency analysis, and significant difference tests, we found that 45% of students thought their physical well-being during the COVID-19 outbreak worsened compared to pre-pandemic times.