Publications by authors named "Mateusz Fiema"
Article Synopsis
- Nearly 48% of COVID-19 patients on ventilators develop ventilator-associated pneumonia (VAP), partly due to harmful changes in oral microbiota. The study aimed to see if a tooth brushing protocol could reduce this risk.
- After studying 56 patients, significant dysbiosis was observed, with high levels of harmful bacteria like Acinetobacter baumannii and Klebsiella pneumoniae, linked to high rates of hospital-acquired infections (HAI).
- Although tooth brushing reduced the presence of these bacteria in the mouth, it did not lower the overall incidence of HAIs, highlighting the complexity of infection sources in ICU settings.
Background: Diabetes is a risk factor for a severe course of COVID-19. We evaluated the characteristics and risk factors associated with undesirable outcomes in diabetic patients (DPs) hospitalized due to COVID-19.
Materials And Methods: The data analysis of patients admitted between March 6, 2020, and May 31, 2021, to the University Hospital in Krakow (Poland), a reference center for COVID-19, was performed.
Objective: The oral microbiota is a very complex and dynamic microbial ecosystem. Alterations of its balance can result in oral and systemic diseases. We aimed to characterize the microbiota in particular niches of the oral cavity in adult type 1 diabetes patients treated with continuous infusion of insulin with insulin pump (IP).
View Article and Find Full Text PDFPurpose: COVID-19 has brought many challenges for providing quality healthcare for type 1 diabetes (T1DM). We evaluated the impact of the COVID-19 pandemic on the medical care, glycemic control, and selected outcomes in T1DM patients.
Methods: We retrospectively analyzed medical records from 357 T1DM adults enrolled in the Program of Comprehensive Outpatient Specialist Care at the University Hospital in Krakow, and assessed differences in patient data from before the COVID-19 period (March 2019-February 2020) and after it started COVID-19 (March 2020-February 2021).
Potential interactions between the SARS-CoV-2 virus and the human oral microbiota are currently investigated widely. Patients with COVID-19 requiring mechanical ventilation in an intensive care unit (ICU) setting are at high risk of developing severe complications, including ventilator-associated pneumonia, thus making oral health management important. The aim of this study was to evaluate the oral health status and assess the dysbiosis of cultivable oral bacteriota in COVID-19 patients hospitalized in an ICU with acute respiratory distress within 36 h following intubation.
View Article and Find Full Text PDFCoinfections between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory pathogens such as have become challenging, as well as being associated with high morbidity and mortality in patients with COVID-19. is a common environmental mold. Before the emergence of COVID-19, it was considered a very rare cause of invasive pulmonary aspergillosis (IPA), occurring mainly in immunocompromised patients.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to identify neurological symptoms in COVID-19 patients during their first 14 days of hospitalization and how these symptoms relate to mortality rates.
- Out of 200 patients, 84.5% experienced neurological symptoms like fatigue, decreased mood, and muscle weakness, with notable differences between those who survived and those who died.
- Key findings revealed that older patients with severe symptoms like decreased consciousness and strokes had a higher mortality risk, suggesting the importance of monitoring neurological signs in COVID-19 patients.
A significant number of patients with Gaucher disease (GD) suffer from chronic or acute pain that reduces their quality of life. A mutation in lysosomal enzyme β-glucosidase (GCase) leads to an accumulation of glucocerebroside in the macrophage-lineage cells, causing the development of clinical symptoms. Novel studies have revealed that ambroxol (trans-4-(2-amino-3,5-dibromobenzylamino)-cyclohexanol), the well-known mucolytic drug, acts as a chaperone for the mutant, misfolded enzyme.
View Article and Find Full Text PDFIntroduction: Long-term poor metabolic control promotes the occurrence of microvascular complications, such as cardiovascular autonomic neuropathy (CAN) and atherogenic hyperlipidaemia, which translates into increased mortality in patients with type 1 diabetes mellitus (T1DM). The aim of the study was to assess the prevalence of CAN in patients with T1DM in relation to treatment method (continuous subcutaneous insulin infusion, CSII, versus multiple daily injections using pens, MDI) and metabolic control.
Material And Methods: The study group comprised 93 adults (60 women, 33 men), mean age 31 years, with T1DM being treated at a local clinical centre from 2011 to 2015.