Publications by authors named "Mateusz A Mazdziarz"
Article Synopsis
- Bisphenol A (BPA) is an endocrine-disrupting chemical commonly found in plastics, linked to serious health issues like cancer, obesity, and kidney dysfunction.
- Recent research studied the effects of BPA on the kidneys of female mice, comparing a group exposed to BPA with a control group.
- The analysis revealed 433 differentially expressed genes, indicating that BPA disrupts essential kidney processes, particularly affecting mitochondrial function and increasing oxidative stress.
Bisphenol A (BPA) is an environmental toxin widely used in the production of polycarbonate plastics. A correlation exists between BPA tissue contamination and the occurrence of pathological conditions, including cancer. First-passage detoxification of high BPA amounts in the liver promotes hepatotoxicity and morphological alterations of this organ, but there is a lack of knowledge about the molecular mechanisms underlying these phenomena.
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