Publications by authors named "Mateus Sabaini Venazzi"
Detection of Leishmania (Viannia) IN Nyssomyia neivai and Nyssomyia whitmani by multiplex polymerase chain reaction, in Southern Brazil.
Herintha Coeto Neitzke-Abreu Kárin Rosi Reinhold-Castro Mateus Sabaini Venazzi Regiane Bertin de Lima Scodro Alessandra de Cassia Dias
Rev Inst Med Trop Sao Paulo
April 2015
Article Synopsis
- * Researchers collected sandflies using traps and analyzed them for signs of infection through dissection and multiplex PCR testing.
- * Findings showed low levels of Leishmania DNA in specific sandfly species (Ny. neivai and Ny. whitmani), indicating their susceptibility to infection and highlighting the multiplex PCR method as a valuable tool for epidemiological research.
This case report alerts to the existence of atypical forms of cutaneous leishmaniasis (CL). A woman with nodular cutaneous lesions over a neck with papules and pustules located deep in the hypodermis that formed plaques with subcutaneous induration and satellite papules was confirmed to have CL. After confirmation, the patient was treated with remission of the lesions, scarring and thickening of the skin.
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- * The study evaluated the effectiveness of polymerase chain reaction (PCR) tests on skin lesion samples (PCR-L) and blood samples (PCR-B) and compared their accuracy to traditional methods, like direct search and skin tests, in a sample of 276 suspected CL patients.
- * Results showed that both PCR methods had higher positivity rates than conventional tests, indicating PCR-L is beneficial for chronic lesions and reinfections, while PCR-B is useful for cases with negative conventional tests or without visible lesions.