Publications by authors named "Mateus Grellert"
Background: The increase in severe traumatic brain injury (sTBI) incidence is a worldwide phenomenon, resulting in a heavy disease burden in the public health systems, specifically in emerging countries. The shock index (SI) is a physiological parameter that indicates cardiovascular status and has been used as a tool to assess the presence and severity of shock, which is increased in sTBI. Considering the high mortality of sTBI, scrutinizing the predictive potential of SI and its variants is vital.
View Article and Find Full Text PDFThe identification of factors associated with 25-hydroxycholecalciferol (25(OH)D) concentration can help suggest more specific interventions for older adults. In this cross-sectional study of older adults from southern Brazil, we hypothesized that some sociodemographic, behavioral, and health factors positively or negatively influence the 25(OH)D concentration in this population. This analysis was performed using data from the second wave of the EpiFloripa Aging Cohort Study (2013-2015).
View Article and Find Full Text PDFObjective: The current study assesses whether the association between diagnosis of Bipolar Disorder (BD) in mothers and emotional and behavioral problems (EBP) in their offspring is mediated by a disruption in the offspring's biological rhythms.
Methods: A probabilistic sample of 492 public school children (ages 7-8, 48 % female) were assessed for biological rhythms disruption and EBP using the Biological Rhythms Interview for Assessment in Neuropsychiatry for Kids and the Strengths and Difficulties Questionnaire, respectively. Mothers' mental health (BD = 64) was evaluated using a standardized clinical interview.
Article Synopsis
- Research explored how temperament traits impact bipolar disorder (BD) and their connection to genetic variations in the CACNA1C gene, particularly in relation to biological sex.
- A study of 878 Caucasian individuals aged 18-35 in Brazil found that certain temperament traits mediated the relationship between specific genetic polymorphisms and BD, particularly in women.
- The results suggested that temperament traits function as endophenotypes for BD in females, but no effects were observed in cisgender men, highlighting a sex-specific interaction in the genetic-temperament-BD link.
Article Synopsis
- Childhood trauma can lead to lasting changes in immune response, particularly through the pro-inflammatory cytokine IL-1β.
- A study with 325 young adults in Brazil found that higher IL-1β levels are linked to greater trauma severity, with anger significantly influencing these levels, especially in men.
- The research highlights how temperament traits, like anger and sensitivity, can modulate the effects of childhood trauma on inflammation in young adults.