Publications by authors named "Matej Maly"

Article Synopsis
  • This study examines how dried plant material can be used to make tea, analyzing three different cultivars.
  • Researchers used advanced techniques to measure the transfer of 42 cannabinoids and 12 bioactive compounds into the tea infusion.
  • Adding cream during steeping significantly enhanced the absorption of these compounds, particularly Δ-THC, potentially leading to high levels that exceed safety guidelines for consumption.
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Phytocannabinoids occurring in Cannabis Sativa L. are unique secondary metabolites possessing interesting pharmacological activities. In this study, the dynamics of thermally induced (60 and 120 °C) phytocannabinoid reactions in four cannabis varieties were investigated.

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Cannabidiol (CBD), together with its precursor cannabidiolic acid (CBDA), is the major phytocannabinoid occurring in most hemp cultivars. To ensure the safe use of these compounds, their effective isolation from hemp extract is required, with special emphasis on the elimination of ∆-tetrahydrocannabinol (∆-THC) and ∆-tetrahydrocannabinolic acid (∆-THCA-A). In this study, we demonstrate the applicability of fast centrifugal partition chromatography (FCPC) as a challenging format of counter-current preparative chromatography for the isolation of CBD and CBDA free of psychotropic compounds that may occur in Cannabis sativa L.

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