[Clinical and epidemiological characteristics of hymenolepiasis in the Ivano-Frankovsk region].

Based on their retrospective epidemiological analysis and examination of 56 outpatient case histories, the authors have studied the clinical and epidemiological regularities of hymenolepiasis in the Ivano-Frankovsk region, which is characterized by: 1) its epidemic and familial pattern, mainly afflicting rural populations, young schoolchildren in particular; 2) high contagiousness and incidence of multiinvasions in the tense foci; 3) a number of the most typical syndromes identified in the clinical picture of helminthic infections, which may serve as criteria for selecting patients for laboratory studies.

[The clinico-immunological characteristics of viral hepatitis A in adolescent girls].

A study of viral hepatitis A in adolescent girls revealed the effect of menstrual cycle phases on the character of the course of the disease. It was established that the critical point of unfavourable course of the disease is coincidence of the days of height of the disease with the follicular peak of estrogen secretion (8-10 day of the cycle). During this period the patients showed a significant quantitative and functional insufficiency of the T-lymphocytic system of immunity and the functional liver tests were highly pathologic.

[The efficacy of the hormonal substitute therapy of adolescents with viral hepatitis A combined with thyroid hypofunction].

Inclusion of thyroidin in the complex therapy of patients with viral hepatitis A and concomitant thyroid pathology accompanied by hypofunction of the thyroid gland produced a positive clinical effect, effected favourably the functional activity of the liver, the immunological and hormonal status. Thyroidin is recommended for wider use in this category of patients.

[The effect of viral hepatitis A on thyroid function in adolescents with thyroid pathology].

In patients with virus hepatitis (VHA) without thyroid pathology, thyroid function decreases but during the recovery, it rapidly restores. In the presence of concomitant thyroid hyperplasia, its function in the acute period of VHA is inhibited to an ever greater degree and remains decreased during convalescence. This circumstance requires the use of replacement hormonal therapy.

[Characteristics of viral hepatitis A and B in adolescents with thyroid pathology].

The combination of viral hepatitis (VH) with thyroid pathology in adolescents leads to an unfavorable course of VH and thyroid disease. The frequency of severe and lingering types of VH with more profound and prolonged shifts of indices of the T- and B-systems of immunity, function of the liver and protein metabolism is increased. Function of the thyroid is sharply suppressed, its euthyroid hyperplasia is often transformed into clinically obvious hypothyroidism.